My primary research interest is understanding the mechanisms allowing efficient symbiotic associations between plants and microbes, and applying this knowledge to maximize the benefits of such associations in agriculture. My specific goals are to (1) understand the genetic and molecular mechanisms allowing the establishment of mycorrhizal and nitrogen-fixing associations, (2) study the evolution of these mechanisms in order to identify critical innovations that allowed the development of these associations, and (3) use this knowledge to engineer more efficient associations (between non-leguminous crops and nitrogen-fixing bacteria in particular) in order to improve the sustainability of our agriculture for food, feed and biofuel production.
- Nitrogen Fixation
Current N-related Projects:
- Evolution of nodule-forming symbioses and improvement of nitrogen fixation in non-leguminous crops
Marx H, Minogue CE, Jayaraman D, Richards AL, Kwiecien NW, Sihapirani AF, Rajasekar S, Maeda J, Garcia K, Del Valle-Echevarria AR, Volkening J, Westphall MS, Roy S, Sussman MR, Ané JM, Coon JJ (2016). A Proteomic Atlas of the Legume, Medicago truncatula, and its Nitrogen-Fixing Endosymbiont, Sinorhizobium meliloti. Nature Biotechnology 34, 1198–1205.
Mus F, Crook M, Garcia K, Garcia-Costas A, Geddes B, Kouri ED, Paramasivan P, Ryu MH, Oldroyd GED, Poole P, Udvardi M, Voigt CA, Ané JM, Peters J (2016). Symbiotic Nitrogen Fixation and Challenges to Extending it to Non-Legumes. Applied and Environmental Microbiology 82(13): 3698–3710.
Gemperline E, Jayaraman D, Maeda J, Ané JM, Li L (2015) Multifaceted Investigation of Metabolites During Nitrogen Fixation in Medicago via High-Resolution MALDI-MS Imaging and ESI-MS. Journal of The American Society for Mass Spectrometry 26(1):149-58.
Venkateshwaran M, Jayaraman D, Chabaud M, Genre A, Balloon AJ, Maeda J, Forshey K, Den Os D, Kwiecien NW, Coon JJ, Barker DG, Ané JM (2015). A role for the mevalonate pathway in early plant symbiotic signaling. Proceedings of the National Academy of Sciences USA 112 (31), 9781-9786.
Barthelemy-Delaux C, Marburger D, Delaux PM, Conley S, Ané JM (2014). Effect of Drought on Bradyrhizobium japonicum Populations in Midwest Soils. Plant and Soil, 382: 165-173.
Venkateshwaran M, Ané JM (2011) Legumes and nitrogen fixation: physiological, molecular, evolutionary perspectives and applications. The Molecular Basis of Nutrient Use Efficiency in Crops (eds Hawkesford M.J. and Barraclough P.B), John Wiley & Sons, Inc., Hoboken, NJ, USA. pp 457-489. ISBN: 978-0-8138-1992-1.